Create a more in vivo-like environment for stem cell culture with Corning Synthemax vitronectin substrate—an animal-free, synthetic, flexible vitronectin-based peptide substrate for serum or serum-free expansion of hPSCs and other adult stem cell types. This surface supports stem cell adhesion and expansion in their undifferentiated state and directed differentiation into specialized cell types. Synthemax vitronectin substrate also offers a synthetic, xeno-free alternative to biological coatings and/or feeder cell layers used in hES and iPS cell culture.
Amendable to coating Corning microcarriers for larger-scale stem cell expansion applications, Synthemax vitronectin substrate allows for:
- Scalable, multi-passage expansion of pluripotent stem cells in serum-free media, such as mTeSR™.
- Differentiation into a number of cell types, including retinal pigment epithelial cells and cardiomyocytes.
- Propagation of various progenitor cell types.